Knoxville, TN (WOKI) UPDATE 12:12 p.m.: Two people are dead and an investigation is underway following a crash Monday morning on I-40 East in West Knoxville.

Knoxville Police Department officials say the single-vehicle crash occurred around 5:30 a.m. near the I-640 East ramp.

KPD says evidence from the scene indicates the involved vehicle was traveling east on the I-40 ramp to I-640 when it ran off the road to the right for reasons that remain unknown, striking a guardrail.

The two occupants, identified as Florida residents, were pronounced dead at the scene.

UPDATE: An investigation is underway after two people are killed in a single vehicle crash on I 40 in West Knoxville. The I-40 East ramp to I-640 East has reportedly reopened following this morning’s crash.

ORIGINAL STORY: An investigation is underway after two people are killed in a single vehicle crash on I 40 in West Knoxville.

As of 11 a.m., the I-40 East ramp to I-640 East is closed temporarily as KPD crash reconstruction personnel remain on scene of this morning’s (Monday) crash. The right lane and shoulder are also blocked.