Pitt quarterback Eli Holstein will be sidelined Saturday against No. 20 Clemson as he continues to recover from apparent head injuries, ESPN reported.

Per the report, Holstein has not been medically cleared after leaving two of the Panthers’ past three games with injuries.

In his place, junior Nate Yarnell will make his fourth career start — first this season — for Pitt.

Yarnell has appeared in 12 games for the Panthers and is 2-1 as a starter. He has completed 65.3 percent (81 of 124) of his passes for 1,104 yards with 10 touchdowns and three interceptions in his career.

In six games this season, he has thrown for 314 yards, five touchdowns and two interceptions.

Holstein won the starting job in training camp. A transfer from Alabama, Holstein has a completion rate of 61.9 percent (177 of 286) and thrown for 2,177 yards with 17 TDs and six interceptions in nine games.

He is also Pitt’s second-leading rusher with 323 yards and three touchdowns.

The Atlantic Coast Conference foes both are 7-2 on the season. Pitt is 3-2 in ACC games; Clemson is 6-1.